Stabile D E, Jacobs A M
Deaconess Hospital, St. Louis, MO.
J Am Podiatr Med Assoc. 1990 Jul;80(7):354-9. doi: 10.7547/87507315-80-7-354.
The authors presented an overview of the development of antibiotic-loaded bone cement beads and their indications for usage, method of application, advantages, disadvantages, and causes of failure. This method of treatment for bone and soft tissue infections of the foot is not a panacea and should be used only in selected cases. The vascular status and the physiologic ability of the patient to heal a peripheral wound or infection are the basis for the success of this method of therapy. European literature makes little mention of adjunctive systemic antibiotic therapy with local antibiotic-loaded bone cement bead use. It is the authors' opinion that clinical judgment should be used to determine the necessity for such therapy.
作者概述了载抗生素骨水泥珠的发展、其使用指征、应用方法、优点、缺点及失败原因。这种治疗足部骨与软组织感染的方法并非万灵药，仅应在特定病例中使用。患者的血管状况及愈合周围伤口或感染的生理能力是该治疗方法成功的基础。欧洲文献很少提及在使用局部载抗生素骨水泥珠时辅助全身性抗生素治疗。作者认为，应运用临床判断来确定这种治疗的必要性。
