Jacobs A M, Seifert A M, Kirisits T J, Protzel H R
Department of Podiatric Medicine and Surgery, Deaconess Hospital, St. Louis, Missouri.
Clin Podiatr Med Surg. 1990 Jul;7(3):523-44.
Antibiotic-loaded bone cement is a useful adjunct in the management of chronic osteomyelitis and in the prevention of recurrent osteomyelitis after an initial attack. Additionally, antibiotic-loaded bone cement stimulated the formation of granulation tissue in excess of that which would normally be expected. Our experience has been consistent with others' experience, which suggests that the use of antibiotic-loaded bone cement is an effective means of reducing the length of hospitalization and the cost usually associated with traditional methods in the management of bone and soft-tissue infections.