Gotoh T, Kubota M, Asano Y, Nonomura K, Togashi M, Koyanagi T
Department of Urology, Hokkaido University School of Medicine.
Nihon Hinyokika Gakkai Zasshi. 1990 Apr;81(4):561-8. doi: 10.5980/jpnjurol1989.81.561.
By the recent advance in ultrasonography, an increasing number of patients with prenatally detected urological anomalies have been reported. Herein, we present 19 cases experienced in the last 3 years in our institution and review the problems in their diagnosis and treatment. In all cases but 2 ultrasonography revealed fetal abnormalities after the 30th gestational week. No cases with abnormal amniotic fluid or severe fetal growth retardation were experienced. No cases were treated in utero. However, 7 cases required an early delivery because of progressive hydronephrosis or enlargement of tumor mass. Postnatally 6 cases were treated by emergency drainage such as percutaneous nephrostomy and placement of an indwelling catheter. However most of the cases with proven urinary tract dilatation were evaluated by diuretic renogram and followed conservatively thereafter. In equivocal cases, pressure-flow study was added. Spontaneous involution of multicystic kidney was also experienced. Erroneous interpretation can occur in fetal diagnosis and the accuracy of prenatal diagnosis was 52.6% in our series. In determining the management of prenatally detected urological anomalies, several factors such as reliability of ultrasonography, fetal renal function, maturity of the lung and the volume of amniotic fluid, must be taken into consideration. Considering the increasing number of fetuses thus detected, it is very important for the pediatric urologists to make consensus on the fetal intervention and postnatal management.
随着超声检查技术的最新进展,已有越来越多产前检测出泌尿系统异常的患者被报道。在此,我们介绍本机构在过去3年中遇到的19例病例,并回顾其诊断和治疗中存在的问题。除2例病例外,所有病例的超声检查均在妊娠30周后发现胎儿异常。未遇到羊水异常或严重胎儿生长受限的病例。没有病例在子宫内接受治疗。然而,7例因进行性肾积水或肿瘤肿块增大而需要提前分娩。出生后,6例通过经皮肾造瘘术和留置导管等紧急引流方法进行治疗。然而,大多数经证实存在尿路扩张的病例通过利尿肾图进行评估,随后进行保守治疗。在诊断不明确的病例中,增加了压力-流量研究。还遇到了多囊肾的自然消退情况。胎儿诊断可能会出现错误解读,在我们的系列研究中,产前诊断的准确率为52.6%。在确定产前检测出的泌尿系统异常的处理方法时,必须考虑超声检查的可靠性、胎儿肾功能、肺成熟度和羊水量等几个因素。鉴于如此检测出的胎儿数量不断增加,小儿泌尿外科医生就胎儿干预和出生后管理达成共识非常重要。