Infectious Disease Service, Infection Control, Department of Medicine, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, NY 10065, USA.
Clin Infect Dis. 2011 Nov;53(10):1003-6. doi: 10.1093/cid/cir643. Epub 2011 Oct 5.
Molecular typing was used to examine surveillance definitions for recurrent Clostridium difficile-associated diarrhea. Among 102 patients, 85 had a second episode within 8 weeks, 88% of which were relapses. Of 49 second episodes occurring after > 8 weeks, 65% were relapses. Categorization of a recurrent episode occurring after >8 weeks as a new infection may misrepresent the majority of episodes for surveillance.
分子分型被用于检查复发性艰难梭菌相关性腹泻的监测定义。在 102 名患者中,85 名在 8 周内出现第二次发作,其中 88%为复发。在 >8 周后发生的 49 例第二次发作中,65%为复发。将 >8 周后发生的复发性发作归类为新感染可能会对监测中的大多数发作产生误导。