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为室间隔完整的大动脉转位晚期患者进行导管再通和支架置入术。

Ductal recanalization and stenting for late presenters with TGA intact ventricular septum.

作者信息

Kothari Shyam S, Ramakrishnan Sivasubramanian, Senguttuvan Nagendra Boopathy, Gupta Saurabh Kumar, Bisoi Akshay K

机构信息

Department of Cardiology, All India Institute of Medical Sciences, New Delhi, India.

出版信息

Ann Pediatr Cardiol. 2011 Jul;4(2):135-8. doi: 10.4103/0974-2069.84651.

Abstract

INTRODUCTION

The ideal management strategy for patients presenting late with transposition of great arteries (TGA), intact ventricular septum (IVS), and regressed left ventricle (LV) is not clear. Primary switch, two-stage switch, and Senning operation are the options. Left ventricular retraining prior to arterial switch by ductal stenting may be effective, but the experience is very limited.

METHODS

Five of six children aged 3-6 months with TGA-IVS and regressed LV underwent recanalization and transcatheter stenting of ductus arteriosus. The ductal stent was removed during arterial switch surgery.

RESULTS

The procedure was successful in 5/6 patients. All the patients had totally occluded ductus and needed recanalization with coronary total occlusion hardware. The ductus was dilated and stented with coronary stents. In all the patients, there was significant luminal narrowing despite adequate stent placement and deployment. Two patients needed reintervention for abrupt closure of the stent. Ductal stenting resulted in left ventricular preparedness within 7-14 days. One patient died of progressive sepsis after 14 days of stenting, even though the LV was prepared. Four patients underwent successful uneventful arterial switch surgery. During surgery, it was observed that the mucosal folds of duct were protruding through the struts of the stent in one patient.

CONCLUSIONS

Ductal stenting is a good alternative strategy for left ventricular retraining in TGA with regressed LV even in patients with occluded ducts.

摘要

引言

对于大动脉转位(TGA)、室间隔完整(IVS)且左心室(LV)退化的晚期就诊患者,理想的管理策略尚不清楚。主要选择包括一期Switch手术、两期Switch手术和森宁手术。在动脉Switch手术前通过导管支架进行左心室再训练可能有效,但经验非常有限。

方法

6例年龄3至6个月的TGA-IVS且LV退化的患儿中,5例接受了动脉导管再通和经导管支架置入术。在动脉Switch手术期间取出导管支架。

结果

该手术在5/6的患者中成功。所有患者的动脉导管均完全闭塞,需要使用冠状动脉完全闭塞器械进行再通。动脉导管用冠状动脉支架进行扩张和支架置入。在所有患者中,尽管支架放置和展开充分,但仍存在明显的管腔狭窄。2例患者需要再次干预以处理支架突然闭塞的情况。导管支架置入术在7至14天内使左心室得到准备。1例患者在支架置入14天后死于进行性脓毒症,尽管左心室已做好准备。4例患者成功进行了顺利的动脉Switch手术。手术期间,观察到1例患者的动脉导管黏膜皱襞穿过支架支柱突出。

结论

对于LV退化的TGA患者,即使动脉导管闭塞,导管支架置入术也是左心室再训练的一种良好替代策略。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c3db/3180970/c8c7c76aa4c0/APC-4-135-g001.jpg

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