Fragulidis Gp, Chondrogiannis Kd, Lykoudis Pm, Karakatsanis A, Georgiou Ca, Vouza E, Melemeni A
Department of Surgery, Aretaieio Hospital, Medical School, University of Athens, Athens, Greece.
J Cutan Aesthet Surg. 2011 May;4(2):132-4. doi: 10.4103/0974-2077.85039.
Granular cell tumour (GCT), also known as Abrikossoff tumour, is an uncommon neoplasm, probably of neural origin derived from Schwann cells. It usually presents as a subcutaneous solitary asymptomatic nodule. It has been the subject of much debate in the literature concerning the tumour origin and the association with other malignancies. We report a case of subcutaneous GCT in the lumbar region in a 31-year-old Caucasian male. Although they are a rare entity, GCTs should be considered in the differential diagnosis of the subcutaneous soft tissue tumours. Surgical removal with wide margins is the treatment of choice as malignant changes have been reported after long-term follow-up.
颗粒细胞瘤(GCT),也称为阿布里科索夫瘤,是一种罕见的肿瘤,可能起源于神经,由施万细胞衍生而来。它通常表现为皮下孤立的无症状结节。关于肿瘤起源以及与其他恶性肿瘤的关联,该肿瘤在文献中一直是诸多争论的主题。我们报告一例31岁白种男性腰部皮下颗粒细胞瘤病例。尽管颗粒细胞瘤是一种罕见的实体瘤,但在皮下软组织肿瘤的鉴别诊断中应考虑到它。由于长期随访后有恶变的报道,因此手术广泛切除是首选的治疗方法。