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胸壁颗粒细胞瘤:细针穿刺抽吸活检诊断及文献复习与细胞学模拟物阐述

Granular Cell Tumour of the Chest Wall: FNA Diagnosis with a Review of Literature and Elaboration of Cytological Mimickers.

作者信息

Choudhary Zeba, Gupta Prajwala, Malhotra Purnima, Bhardwaj Minakshi, Sharma Prafull Kumar

机构信息

Senior Resident, Department of Pathology, Pgimer, Dr. Ram Manohar Lohia Hospital, New Delhi, India.

Associate Professor, Department of Pathology, Pgimer, Dr. Ram Manohar Lohia Hospital, New Delhi, India.

出版信息

J Clin Diagn Res. 2017 Aug;11(8):ED01-ED03. doi: 10.7860/JCDR/2017/29123.10337. Epub 2017 Aug 1.

Abstract

Granular Cell Tumours (GCTs) are uncommon tumours which can be confused with other benign soft tissue tumours on clinical examination. Fine Needle Aspiration Cytology (FNAC) plays a significant role in their diagnosis. There are certain cytological mimickers of GCTs so a cytopathologist must be aware of its characteristic cytomorphology. These tumours can be present anywhere on the body; however, chest wall is one of the uncommon sites. We present a case of GCT present on the chest wall in an elderly male as a subcutaneous nodule. We have discussed the common cytological differential of GCTs, features of malignant GCTs along with cytomorphological and immunohistochemical features.

摘要

颗粒细胞瘤(GCTs)是一种罕见肿瘤,在临床检查中可能会与其他良性软组织肿瘤相混淆。细针穿刺抽吸细胞学检查(FNAC)在其诊断中起着重要作用。存在一些GCTs的细胞学模仿者,因此细胞病理学家必须了解其特征性细胞形态。这些肿瘤可出现在身体的任何部位;然而,胸壁是不常见的部位之一。我们报告一例老年男性胸壁出现的GCT,表现为皮下结节。我们讨论了GCTs常见的细胞学鉴别诊断、恶性GCTs的特征以及细胞形态学和免疫组化特征。

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本文引用的文献

1
Fine-needle aspiration cytology of granular cell tumor: A report of two cases.
J Cytol. 2013 Jul;30(3):195-7. doi: 10.4103/0970-9371.117641.
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3
Granular cell tumor occurring in the chest wall: a case report.发生于胸壁的颗粒细胞瘤:1例报告
Korean J Thorac Cardiovasc Surg. 2012 Jun;45(3):196-8. doi: 10.5090/kjtcs.2012.45.3.196. Epub 2012 Jun 7.
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Alveolar soft-part sarcoma: a review and update.肺泡软组织肉瘤:综述与更新
J Clin Pathol. 2006 Nov;59(11):1127-32. doi: 10.1136/jcp.2005.031120.
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Fine-needle aspiration characteristics of hibernoma.冬眠瘤的细针穿刺特征
Cancer. 2001 Jun 25;93(3):206-10. doi: 10.1002/cncr.9030.
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Fine needle aspiration cytology (FNAC) of mammary granular cell tumour: a report of three cases.
Cytopathology. 1999 Dec;10(6):383-9. doi: 10.1046/j.1365-2303.1999.00201.x.

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