Choudhary Zeba, Gupta Prajwala, Malhotra Purnima, Bhardwaj Minakshi, Sharma Prafull Kumar
Senior Resident, Department of Pathology, Pgimer, Dr. Ram Manohar Lohia Hospital, New Delhi, India.
Associate Professor, Department of Pathology, Pgimer, Dr. Ram Manohar Lohia Hospital, New Delhi, India.
J Clin Diagn Res. 2017 Aug;11(8):ED01-ED03. doi: 10.7860/JCDR/2017/29123.10337. Epub 2017 Aug 1.
Granular Cell Tumours (GCTs) are uncommon tumours which can be confused with other benign soft tissue tumours on clinical examination. Fine Needle Aspiration Cytology (FNAC) plays a significant role in their diagnosis. There are certain cytological mimickers of GCTs so a cytopathologist must be aware of its characteristic cytomorphology. These tumours can be present anywhere on the body; however, chest wall is one of the uncommon sites. We present a case of GCT present on the chest wall in an elderly male as a subcutaneous nodule. We have discussed the common cytological differential of GCTs, features of malignant GCTs along with cytomorphological and immunohistochemical features.
颗粒细胞瘤(GCTs)是一种罕见肿瘤,在临床检查中可能会与其他良性软组织肿瘤相混淆。细针穿刺抽吸细胞学检查(FNAC)在其诊断中起着重要作用。存在一些GCTs的细胞学模仿者,因此细胞病理学家必须了解其特征性细胞形态。这些肿瘤可出现在身体的任何部位;然而,胸壁是不常见的部位之一。我们报告一例老年男性胸壁出现的GCT,表现为皮下结节。我们讨论了GCTs常见的细胞学鉴别诊断、恶性GCTs的特征以及细胞形态学和免疫组化特征。