[A favorable hyperlipoproteinemia: high-density lipoproteins and atherosclerosis].

A full, clinical appreciation of blood cholesterol levels necessitates recognition of the divergent influences of cholesterol associated with low density lipoprotein (atherogenic) and high density lipoproteins (HDL, anti-atherogenic) on the atherosclerotic process. Convincing evidence now exists to show that raising HDL-cholesterol levels reduces the incidence of cardiovascular disease, thus providing a firm rationale for therapeutic measures designed to favourably modify its plasma concentrations. In this respect, association of lower HDL-cholesterol levels with an unhealthy life style (smoking, lack of exercise, obesity) is of particular relevance. Whilst still a subject of discussion, available data strongly support the inclusion of HDL-cholesterol measurements when establishing plasma lipid profiles.