Division of Cardiovascular Diseases, Department of Internal Medicine, Mayo Clinic and Foundation, Rochester, MN, USA.
Sleep Med. 2011 Oct;12(9):924-7. doi: 10.1016/j.sleep.2010.11.014. Epub 2011 Oct 5.
Obstructive sleep apnea (OSA) has been recognized as a risk factor for cardiovascular disease and mortality. The aim of this study was to determine the feasibility and efficacy of implementing a screening program for OSA in early outpatient cardiac rehabilitation (CR) and to estimate the risk for OSA in this population.
From 535 consecutive patients enrolled in early outpatient CR we screened 383 (72%) patients and classified them as low- vs. high-risk for OSA using the Berlin questionnaire. Those considered at high-risk for OSA were referred for further evaluation. We assessed the yield and feasibility of the screening program, patient compliance with referral, and the percentage of patients diagnosed with OSA after polysomnography.
Mean age was 63 ± 12 years, 70% were men, 20% had diabetes, 65% had hypertension, and 58% had experienced a recent myocardial infarction. Two hundred and one patients (52%) had a high risk for OSA based on the questionnaire. Of the 169 who completed the CR program, only 111 (78%) were referred for further evaluation (Fig. 1). Of the 74 patients who completed their OSA work-up, 39 were found to have OSA with an apnea-hypopnea index of ≥ 5 events/h.
Implementation of a simple screening program for OSA in early outpatient CR is feasible with minimal incremental resources. A significant percentage of patients at high-risk decline further evaluation, suggesting that their perceived risk for OSA and its consequences may be low.
阻塞性睡眠呼吸暂停(OSA)已被认为是心血管疾病和死亡率的一个风险因素。本研究的目的是确定在早期门诊心脏康复(CR)中实施 OSA 筛查计划的可行性和疗效,并估计该人群中 OSA 的风险。
我们从 535 名连续入组早期门诊 CR 的患者中筛查了 383 名(72%)患者,并使用柏林问卷将他们分为低风险和高风险 OSA。那些被认为有高风险 OSA 的患者被转介进行进一步评估。我们评估了筛查计划的收益和可行性、患者对转介的依从性以及经过多导睡眠图诊断为 OSA 的患者比例。
平均年龄为 63 ± 12 岁,70%为男性,20%患有糖尿病,65%患有高血压,58%经历过近期心肌梗死。根据问卷,201 名患者(52%)有高风险 OSA。在完成 CR 项目的 169 名患者中,仅有 111 名(78%)被转介进行进一步评估(图 1)。在完成 OSA 评估的 74 名患者中,有 39 名被发现患有 OSA,其呼吸暂停低通气指数≥5 次/小时。
在早期门诊 CR 中实施简单的 OSA 筛查计划是可行的,只需增加最少的资源。很大一部分高风险患者拒绝进一步评估,这表明他们对 OSA 及其后果的感知风险可能较低。