Moghadam Katayoun G, Khashayar Patricia, Hashemi Mahmoodreza
Department of Pathology, 501 hospital, Tehran, Iran.
Acta Med Indones. 2011 Jul;43(3):191-4.
Strongyloides stercoralis is an intestinal nematode, endemic in tropical countries. The parasite has a complex life cycle, causing a long-lived auto infection in hosts. It may remain asymptomatic or with minor symptoms; the dormant carrier state of the illness may persist for a long period of time. Inflammatory bowel disease (IBD) including Crohn's disease (CD) and ulcerative colitis (UC), commonly treated with immunosuppressive drugs is a well-known condition predisposing individuals to various infections. The condition is more prevalent among immunocompromised patients; the diagnosis of which, however, is troublesome in such individuals. The present article reports a 45- year-old female with gastric strongyloides stercoralis infection while receiving the treatment for her underlying UC. Strongyloides stercoralis can easily be missed especially in IBD patients in the absence of accompanying diarrhea or any symptom of lower GI discomfort because it presents with various manifestations including multiple GI symptoms, multiple stool exams and special attention to peripheral eosinophilia are specially important but not so sensitive or specific.
粪类圆线虫是一种肠道线虫,在热带国家流行。该寄生虫具有复杂的生命周期,可在宿主体内引起长期的自身感染。它可能无症状或仅有轻微症状;疾病的潜伏携带状态可能持续很长时间。炎症性肠病(IBD)包括克罗恩病(CD)和溃疡性结肠炎(UC),通常用免疫抑制药物治疗,是一种众所周知的使个体易患各种感染的疾病。这种情况在免疫功能低下的患者中更为普遍;然而,在这类个体中进行诊断很麻烦。本文报道了一名45岁女性,在接受基础UC治疗时感染了胃粪类圆线虫。粪类圆线虫很容易被漏诊,尤其是在没有伴随腹泻或任何下消化道不适症状的IBD患者中,因为它有多种表现,包括多种胃肠道症状,多次粪便检查以及特别关注外周嗜酸性粒细胞增多尤为重要,但不太敏感或特异。