Celiloğlu Can, Karabiber Hamza, Selimoğlu Mukadder Ayşe
Department of Pediatrics, Malatya State Hospital, Malatya, Turkey.
Turk J Pediatr. 2011 May-Jun;53(3):241-9.
Celiac disease (CD) has a wide variety of clinical presentations; together with the "classical form", in which the intestinal symptomatology is prevalent, there are "atypical forms" with predominating extra-intestinal clinical features, and the "silent form", with no clinical symptom. The "atypical forms" of the disease are characterized by few or no gastrointestinal symptoms, and predominating extra-intestinal features such as neurologic, dermatologic, hematologic, endocrinologic, reproductive, renal, psychiatric, skeletal, and liver involvement(s). Silent presentation of CD may be identified through screening of high-risk groups. Today, it is well known that CD might account for several chronic health issues, so it is essential for healthcare professionals to have a high level of suspicion for the atypical presentations of CD.
乳糜泻(CD)有多种临床表现;除了以肠道症状为主的“经典型”,还有以肠道外临床表现为主的“非典型型”,以及无临床症状的“隐匿型”。该疾病的“非典型型”特点是胃肠道症状很少或没有,而以肠道外特征为主,如神经、皮肤、血液、内分泌、生殖、肾脏、精神、骨骼和肝脏受累。CD的隐匿表现可通过对高危人群的筛查来识别。如今,众所周知,CD可能是多种慢性健康问题的病因,因此医疗保健专业人员对CD的非典型表现保持高度怀疑至关重要。