Institute of Sport Exercise and Active Learning, Victoria University, Melbourne, Victoria, Australia.
Appl Physiol Nutr Metab. 2011 Oct;36(5):671-81. doi: 10.1139/h11-073. Epub 2011 Oct 7.
This study investigated the effects of high-dose large neutral amino acid (LNAA) supplementation on attenuating fatigue-induced decrements in exercise and motor skill performance in Australian Rules Football (ARF) players. Fifteen subelite ARF players participated in 3 testing sessions separated by 7 days. Players completed an initial control trial involving a reactive motor skills test (RMST) and a reactive agility test (RAT) carried out before and after fatiguing exercise. In the subsequent experimental trials, players ingested a serotonin-depleting or protein control (PC) LNAA mixture 3 h before testing, allocated in a double-blind randomized cross-over design. Blood samples were taken at presupplementation and pre- and postexercise for analysis of plasma amino acid, insulin, and metabolite concentrations. The effect of the LNAA was established as the difference in the change in the mean RMST and RAT test scores among the depleting, PC, and baseline (BL) trials. Mean overall repetition time of the RAT was moderately improved by -5.2% ± 3.4% (mean ± 90% confidence limits; effect size -0.45 ± 0.28) after ingestion of the serotonin-depleting mixture compared with the BL trial. Serotonin-depleting and PC supplements had a divergent effect on mean repetition time after fatiguing exercise in RMST: depleting serotonin elicited a small improvement (-3.0% ± 2.7%) in motor skill performance in contrast to a small decrement (2.4% ± 2.7%) after ingestion of the PC mixture, when compared to the BL. High-dose serotonin-"depleting" LNAA supplementation given 3 h prior to intermittent high-intensity exercise improved reactive motor skill and agility performance in ARF players.
这项研究调查了高剂量大中性氨基酸（LNAA）补充剂对减轻澳大利亚足球（ARF）运动员疲劳引起的运动和运动技能表现下降的影响。15 名次精英 ARF 运动员参加了 3 次测试，每次测试间隔 7 天。运动员完成了初始对照试验，包括反应性运动技能测试（RMST）和反应性敏捷性测试（RAT），在疲劳运动前后进行。在随后的实验试验中，运动员在测试前 3 小时摄入了一种消耗血清素或蛋白质对照（PC）LNAA 混合物，采用双盲随机交叉设计分配。在补充前和运动前后采集血样，用于分析血浆氨基酸、胰岛素和代谢物浓度。LNAA 的作用是通过在消耗、PC 和基线（BL）试验中观察到的 RMST 和 RAT 测试分数变化的差异来确定的。与 BL 试验相比，摄入消耗血清素混合物后，RAT 的平均整体重复时间平均提高了-5.2%±3.4%（平均值±90%置信区间；效应大小-0.45±0.28）。与 BL 试验相比，消耗血清素和 PC 补充剂对 RMST 中平均重复时间有不同的影响：消耗血清素后，运动技能表现略有改善（-3.0%±2.7%），而摄入 PC 混合物后，运动技能表现略有下降（2.4%±2.7%）。在间歇性高强度运动前 3 小时给予高剂量的血清素“消耗”LNAA 补充剂可改善 ARF 运动员的反应性运动技能和敏捷性表现。
