Department of Biology and National Center for Behavioral Genomics, Brandeis University, Waltham, MA 02454, USA.
Neuron. 2011 Oct 6;72(1):3-5. doi: 10.1016/j.neuron.2011.09.017.
In this issue of Neuron, Greenberg and colleagues revise our understanding of how activity-dependent MeCP2 phosphorylation regulates distinct aspects of brain development and circuit function. The study also suggests a prominent role for MeCP2 in the regulation of global chromatin state in vivo.
在本期《神经元》杂志中，Greenberg 及其同事修正了我们对活性依赖性 MeCP2 磷酸化如何调节大脑发育和回路功能不同方面的理解。该研究还表明 MeCP2 在调节体内整体染色质状态方面发挥着重要作用。
