Indian Institute of Technology Guwahati, Department of Chemistry, Guwahati 781 039, Assam, India.
Carbohydr Res. 2011 Nov 29;346(16):2629-32. doi: 10.1016/j.carres.2011.09.006. Epub 2011 Sep 16.
A wide variety of dithioacetal derivatives of sugars can be cleaved easily into the corresponding open-chain aldehydo sugars using an efficient combination of VO(acac)(2)/H(2)O(2)/NaI at 0-5°C. Some of the salient features of this protocol are mild reaction conditions, good yields, short reaction times, easy work-up procedures, and non-involvement of toxic chemicals.
使用 VO(acac)(2)/H(2)O(2)/NaI 的有效组合，在 0-5°C 下，各种糖的二硫缩醛衍生物可以很容易地被裂解成相应的开链醛糖。该方案的一些显著特点是反应条件温和、产率高、反应时间短、后处理操作简单，且不涉及有毒化学品。
