生物膜在严重头颈部感染中起什么作用？
What is the role of biofilms in severe head and neck infections?
作者信息
Ray J Michael, Triplett R Gilbert
机构信息
Department of Oral and Maxillofacial Surgery, Baylor College of Dentistry, Texas A&M Health Science Center, 3302 Gaston Avenue, Dallas, TX 75246, USA.
出版信息
Oral Maxillofac Surg Clin North Am. 2011 Nov;23(4):497-505. v. doi: 10.1016/j.coms.2011.07.002.
Most infections of the head and neck and virtually all of those encountered in the practice of dentistry are caused by bacteria that are organized into biofilms. A biofilm is a complex, usually multispecies, highly communicative community of bacteria that is surrounded by a polymeric matrix. Treatment of these types of infections with traditional antibiotics alone is ineffective, and surgical removal of diseased tissue is still necessary.
头颈部的大多数感染以及牙科实践中几乎所有遇到的感染都是由形成生物膜的细菌引起的。生物膜是一种复杂的、通常由多种物种组成的、高度交流的细菌群落，被一种聚合基质所包围。仅用传统抗生素治疗这类感染是无效的，仍然需要手术切除病变组织。
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