Flynn Thomas R
Oral Maxillofac Surg Clin North Am. 2011 Nov;23(4):519-36, v-vi. doi: 10.1016/j.coms.2011.07.005.
In the everyday practice of oral and maxillofacial surgeons, empiric antibiotics are prescribed in the face of uncertainty. Is there a highly resistant organism present? Are the old-line antibiotics no longer effective? Should a broad-spectrum antibiotic be used just to cover all the bases in this case? The surprising result of this systematic review is that when combined with appropriate surgery, the usual antibiotics are all effective. Safety and cost become the differentiating factors in this clinical decision.
在口腔颌面外科医生的日常实践中，面对不确定性时会开具经验性抗生素。是否存在高度耐药的微生物？传统抗生素是否不再有效？在这种情况下是否应该使用广谱抗生素来全面预防？这项系统评价的惊人结果是，与适当的手术相结合时，常用的抗生素都是有效的。安全性和成本成为这一临床决策中的区别因素。
