Department of Ophthalmology, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.
Am J Ophthalmol. 2012 Feb;153(2):320-326.e1. doi: 10.1016/j.ajo.2011.07.007. Epub 2011 Oct 8.
To compare clinical outcomes after vitrectomy and internal limiting membrane (ILM) peeling, with and without gas tamponade, for the treatment of myopic foveoschisis.
Retrospective, comparative, interventional case series.
In this retrospective clinical study, 17 eyes of 17 consecutive patients underwent vitrectomy and ILM peeling for treatment of myopic foveoschisis. Eyes were divided into 2 groups, those with gas tamponade (n = 9) and those without (n = 8). Gas tamponade was chosen according to the period and surgeon's discretion. The changes of foveal anatomy on preoperative optical coherence tomography (OCT) were not considered in the decision. Main outcome measures were the rate of resolution of myopic foveoschisis measured by OCT, the time interval until resolution of myopic foveoschisis, central foveal thickness, and best-corrected visual acuity (BCVA).
After surgery, OCT showed a resolution of myopic foveoschisis in 8 eyes (88.9%) in the gas-treated group and in 6 eyes (75.0%) in the no-gas group. This difference between the groups was statistically insignificant (P = .576). The mean period until the resolution of myopic foveoschisis was 2.25 months in the gas-treated group and 4.50 months in the no-gas group (P = .011). The mean BCVA improved significantly in both the gas-treated and no-gas groups (P = .011 and P = .017, respectively).
Vitrectomy and ILM peeling without gas tamponade appears to be as effective in the treatment of myopic foveoschisis as vitrectomy with gas tamponade. However, eyes treated with gas tamponade showed more rapid resolution of myopic foveoschisis.
比较伴或不伴气体填充的玻璃体切除术和内界膜(ILM)剥除术治疗近视性黄斑劈裂的临床效果。
回顾性、对比、干预性病例系列研究。
在这项回顾性临床研究中,17 名连续患者的 17 只眼接受了玻璃体切除术和 ILM 剥除术治疗近视性黄斑劈裂。将眼分为两组,一组伴气体填充(n = 9),一组不伴气体填充(n = 8)。气体填充的选择依据是时期和术者的判断。术前光学相干断层扫描(OCT)显示的黄斑解剖结构变化未在决策中考虑。主要观察指标为 OCT 测量的近视性黄斑劈裂的解决率、近视性黄斑劈裂解决的时间间隔、中心黄斑厚度和最佳矫正视力(BCVA)。
术后,OCT 显示气体处理组 8 只眼(88.9%)和无气体组 6 只眼(75.0%)的近视性黄斑劈裂得到解决。两组间差异无统计学意义(P =.576)。气体处理组近视性黄斑劈裂解决的平均时间为 2.25 个月,无气体组为 4.50 个月(P =.011)。气体处理组和无气体组的平均 BCVA 均显著改善(P =.011 和 P =.017)。
不伴气体填充的玻璃体切除术和 ILM 剥除术在治疗近视性黄斑劈裂方面似乎与伴气体填充的玻璃体切除术同样有效。然而,接受气体填充治疗的眼显示出更快的近视性黄斑劈裂解决速度。