University Centre of Legal Medicine, Lausanne-Geneva, Rue du Bugnon 21, 1011, Lausanne, Switzerland.
Int J Legal Med. 2012 Mar;126(2):199-215. doi: 10.1007/s00414-011-0614-1. Epub 2011 Oct 9.
As a continuation of "Postmortem Chemistry Update Part I," Part II deals with molecules linked to liver and cardiac functions, alcohol intake and alcohol misuse, myocardial ischemia, inflammation, sepsis, anaphylaxis, and hormonal disturbances. A very important array of new material concerning these situations had appeared in the forensic literature over the last two decades. Some molecules, such as procalcitonin and C-reactive protein, are currently researched in cases of suspected sepsis and inflammation, whereas many other analytes are not integrated into routine casework. As in part I, a literature review concerning a large panel of molecules of forensic interest is presented, as well as the results of our own observations, where possible.
作为“尸检化学更新第一部分”的续篇,第二部分涉及与肝脏和心脏功能、酒精摄入和滥用、心肌缺血、炎症、败血症、过敏反应和激素紊乱相关的分子。在过去的二十年中,法医文献中出现了大量与这些情况相关的新材料。一些分子,如降钙素原和 C 反应蛋白,目前在疑似败血症和炎症的病例中进行研究,而许多其他分析物并未纳入常规案例工作中。与第一部分一样,本文介绍了广泛的法医感兴趣的分子的文献综述,以及我们自己的观察结果(在可能的情况下)。