Figarella-Branger D, Gambarelli D, Perez-Castillo M, Garbe L, Grisoli F
Department of Neuropathology, Centre Hospitalier Regional, Marseille, France.
Neurosurgery. 1990 Jul;27(1):142-7.
A case of primary intracerebral plasma cell granuloma without meningeal attachment is presented. Histologically, the lesion showed two different patterns. At the center, it displayed the features of a benign fibrous histiocytoma. At the periphery, a mixture of polyclonal plasma cells, lymphocytes, and "epithelial-like" cells was observed. Electron microscopy and immunocytochemistry confirmed the histiocytic nature of the "epithelial-like cells." The differential diagnosis and histogenesis of such a lesion are discussed.
本文报告一例无脑膜附着的原发性脑内浆细胞肉芽肿病例。组织学上，该病变呈现两种不同模式。在病变中心，表现为良性纤维组织细胞瘤的特征。在周边区域，可见多克隆浆细胞、淋巴细胞和“上皮样”细胞的混合。电子显微镜和免疫细胞化学证实了“上皮样细胞”的组织细胞性质。并对这种病变的鉴别诊断和组织发生进行了讨论。
