Ponte E, Panebianco A, Morena S
Cattedra di Angiologia, Università di Trieste.
Minerva Med. 1990 May;81(5):335-40.
This review of the literature is designed to identify the state of our knowledge about the ileal, colonic and biliary damage arising in diabetes mellitus. The approach is primarily clinical with the emphasis on the major symptoms involved: diarrhea, constipation and anal sphincter incontinence. The most common symptom, found in 20% of diabetics with neurological disease, is constipation. While the peculiar features of diabetic diarrhea have been well described, there is considerable controversy over its pathogenesis. As for sphincter dysfunction, manometric examinations will already reveal the autonomic neuropathy involved in the early asymptomatic phase. There is considerable debate over the possible involvement of the gallbladder in diabetes mellitus. Some believe that the autonomic neuropathy is involved in the pathogenesis of the lithiasis and helps to mask the pain in cholecystitis as well.
这篇文献综述旨在明确我们对于糖尿病引发的回肠、结肠和胆道损害的认知状况。研究方法主要是临床研究,重点关注主要相关症状:腹泻、便秘和肛门括约肌失禁。最常见的症状是便秘,在20%患有神经病变的糖尿病患者中出现。虽然糖尿病性腹泻的特殊特征已得到充分描述,但其发病机制仍存在很大争议。至于括约肌功能障碍,测压检查已能揭示早期无症状阶段所涉及的自主神经病变。关于糖尿病中胆囊可能受累存在相当大的争议。一些人认为自主神经病变参与了结石形成的发病机制,并且也有助于掩盖胆囊炎的疼痛。