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对乳腺癌易感性基因检测的风险认知、担忧和态度。

Risk perceptions, worry, and attitudes about genetic testing for breast cancer susceptibility.

机构信息

a Department of Psychology.

出版信息

Psychol Health. 2006;21(2):211-30. doi: 10.1080/14768320500230318.

DOI:10.1080/14768320500230318
PMID:21985118
Abstract

This study assessed the unique associations of risk perceptions and worry with attitudes about genetic testing for breast cancer susceptibility. Women (general practitioner clinic attenders, university students, and first-degree relatives of breast cancer survivors; N = 303) read information about genetic testing and completed measures assessing perceived cancer risk, cancer worry, and genetic testing attitudes and beliefs. Worry was associated with greater interest in genetic testing, stronger beliefs that testing has detrimental emotional consequences, and positive beliefs about benefits of testing and risk-reducing surgeries. Perceived risk was unrelated to interest and associated with more skeptical beliefs about emotional consequences and benefits of testing and risk-reducing surgeries. At low worry levels, testing interest increased with more positive beliefs about testing benefits; at high worry levels, interest was high regardless of benefits beliefs. The findings support Leventhal's Common-Sense Model of self-regulation delineating interactive influences of risk-related cognitions and emotions on information processing and behavior.

摘要

本研究评估了风险认知和担忧与乳腺癌易感性遗传检测相关态度的独特关联。女性(普通科诊所就诊者、大学生和乳腺癌幸存者的一级亲属;N=303)阅读了有关遗传检测的信息,并完成了评估癌症风险感知、癌症担忧和遗传检测态度和信念的测量。担忧与对遗传检测的更大兴趣、更强的检测具有不良情绪后果的信念以及对检测和降低风险手术的益处的积极信念有关。感知风险与兴趣无关,与对检测情绪后果和益处以及降低风险手术的更怀疑的信念有关。在低担忧水平下,随着对检测益处的更多积极信念,检测兴趣增加;在高担忧水平下,无论益处信念如何,兴趣都很高。这些发现支持莱文索尔的自我调节常识模型,该模型描述了风险相关认知和情绪对信息处理和行为的交互影响。

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