Kitada Masahiro, Matsuda Yoshinari, Sato Kazuhiro, Hayashi Satoshi, Ishibashi Kei, Miyokawa Naoyuki, Sasajima Tadahiro
Department of Surgery, Asahikawa Medical University, Asahikawa, Japan.
J Cardiothorac Surg. 2011 Oct 11;6:132. doi: 10.1186/1749-8090-6-132.
Mucoepidermoid carcinoma of the lung (MEC) is a tumor of low malignant potential of bronchial gland origin. MEC and adenoid cystic carcinoma are both considered to be salivary gland-type neoplasms. MECs are comparatively rare with an incidence of all lung cancers. We recently encountered a case of this type of lung cancer. A 60-year-old man was found to have an abnormal shadow in the left lower lung field on a regular check-up for lung cancer at his company. Chest radiography and CT revealed a mass shadow measuring 30 mm in diameter in the left lower lung field. Bronchoscopy revealed a protuberant tumor in the S9 bronchus, leading to a diagnosis of low-grade MEC by transbronchial lung biopsy. He underwent left lower lobe resection and mediastinal lymph node dissection using VATS. Tumor cells had a scattering of mucus-producing epithelial components in papillary growth of stratified squamous epithelia with anisokaryosis and minimal pleomorphism, indicating a diagnosis of MEC. Because the postoperative course was good and the tumor was low-grade, no adjuvant treatment was administered. The patient has had no signs of tumor recurrence for 9 months, to date, since resection of the tumor.
肺黏液表皮样癌（MEC）是一种起源于支气管腺体、恶性潜能较低的肿瘤。MEC和腺样囊性癌均被视为涎腺型肿瘤。MEC在所有肺癌中相对少见。我们最近遇到了一例这种类型的肺癌。一名60岁男性在其公司的肺癌定期检查中，发现左下肺野有异常阴影。胸部X线摄影和CT显示左下肺野有一个直径30mm的肿块阴影。支气管镜检查发现S9支气管有一个突出的肿瘤，经支气管肺活检诊断为低级别MEC。他接受了电视辅助胸腔镜手术（VATS）下的左下叶切除和纵隔淋巴结清扫。肿瘤细胞在分层鳞状上皮的乳头状生长中有散在的产生黏液的上皮成分，伴有核异形和轻度多形性，提示MEC诊断。由于术后过程良好且肿瘤为低级别，未给予辅助治疗。迄今为止，自肿瘤切除以来，该患者9个月来没有肿瘤复发的迹象。
