Department of Medicine, Division of Neurology, Amiri Hospital, Kuwait, Kuwait.
Int J Neurosci. 2012 Feb;122(2):82-7. doi: 10.3109/00207454.2011.630543. Epub 2011 Nov 15.
To study clinical characteristics of multiple sclerosis (MS) patients in Kuwait and to collect data on annual relapse rates and disability measures.
An MS Registry was created in Amiri Hospital. Demographic, clinical characteristics, and disability measures using Expanded Disability Status Scale (EDSS) score at last visit were collected.
Data from 218 patients formed the basis of the study cohort. Female to male ratio was 1.95. Mean age of onset of MS was 26.8 years. Seventy-eight percent had a relapsing-remitting course, 9.2% had secondary progressive course, and 2.8% had primary progressive course. The clinically isolated syndrome (CIS) group constituted 10.1%. The mean disease duration was 8 ± 7.2 years. Forty-five percent of patients had ≤5 years of disease duration, followed by 24.3% and 25.2% in the 5-10 and 10-20 years durations. Only 5.5% had MS for >20 years; 77.1% of patients had <1 relapse per year, while 22% had 1-2 relapses per year; 67.89% of patients had EDSS score <4, whereas 17.89% were found to have EDSS of ≥6.
MS in Kuwait predominantly affects female. The mean age of onset and frequency of MS types are comparable to worldwide figures. The annual relapse rates and the EDSS scores were relatively low in our cohort.
研究科威特多发性硬化症（MS）患者的临床特征，并收集年度复发率和残疾评估数据。
在 Amiri 医院创建了一个 MS 注册处。收集人口统计学、临床特征以及最后一次就诊时使用扩展残疾状态量表（EDSS）评分的残疾评估数据。
该研究队列的数据来源于 218 名患者。男女比例为 1.95。MS 的发病年龄平均为 26.8 岁。78%为复发缓解型病程，9.2%为继发进展型病程，2.8%为原发进展型病程。临床孤立综合征（CIS）组占 10.1%。平均病程为 8 ± 7.2 年。45%的患者病程<5 年，其次是病程为 5-10 年的患者（24.3%）和病程为 10-20 年的患者（25.2%）。仅有 5.5%的患者病程>20 年；77.1%的患者每年复发<1 次，22%的患者每年复发 1-2 次；67.89%的患者 EDSS 评分<4，而 17.89%的患者 EDSS 评分≥6。
科威特的 MS 主要影响女性。发病年龄和 MS 类型的频率与全球数据相当。我们队列的年复发率和 EDSS 评分相对较低。
