Division of Cardiac and Thoracic Surgery, University of Arizona School of Medicine, Phoenix, Arizona, USA.
Curr Opin Cardiol. 2011 Nov;26(6):518-22. doi: 10.1097/HCO.0b013e32834b9f6d.
Endoscopic vein harvest (EVH) has quickly been adopted as the standard-of-care for coronary artery bypass grafting (CABG). Despite clear advantages in terms of wound morbidity, healing, pain, and patient satisfaction, data from recent large clinical trials have called the safety of this technique into question.
Post-hoc analyses of a variety of prospective trials have suggested EVH is associated with decreased graft patency, higher rates of cardiovascular complications (e.g. myocardial infarction, need for repeat revascularization) and mortality. Imaging studies of veins procured by EVH have revealed retained clot and vascular injury, particularly during the 'learning curve' of the technician. These findings may alter the quality of the conduit and, therefore, the outcome of the bypass graft. Elucidating the mechanisms that underlie any differences in results produced by the open and endoscopic procedures would help better inform clinical practice and the development of targeted strategies to improve EVH.
Clear clinical advantages over traditional open vein harvest have allowed EVH to rapidly become the standard-of-care for harvesting of one or more vein grafts during CABG. The quality of these conduits, suggested to be equivalent by early studies, has come into question as groups with varying levels of experience have adopted the endoscopic technique. Elucidating the principles of 'best practice' for vein harvest will likely help shorten the learning curve and improve the safety of EVH.
内镜静脉采集(EVH)已迅速成为冠状动脉旁路移植术(CABG)的标准治疗方法。尽管在伤口发病率、愈合、疼痛和患者满意度方面具有明显优势,但最近的大型临床试验数据对该技术的安全性提出了质疑。
各种前瞻性试验的事后分析表明,EVH 与移植通畅率降低、心血管并发症(如心肌梗死、需要再次血运重建)和死亡率升高有关。对 EVH 采集的静脉进行的影像学研究显示,血管内有血栓和血管损伤,尤其是在技术人员的“学习曲线”期间。这些发现可能会改变移植物的质量,从而影响旁路移植的结果。阐明开放和内镜手术结果存在差异的机制将有助于更好地指导临床实践,并制定有针对性的策略来改进 EVH。
与传统的开放式静脉采集相比,EVH 具有明显的临床优势,使其迅速成为 CABG 中采集一条或多条静脉移植物的标准治疗方法。这些移植物的质量在早期研究中被认为是等效的,但随着经验水平不同的团队采用内镜技术,其质量开始受到质疑。阐明静脉采集的“最佳实践”原则可能有助于缩短学习曲线并提高 EVH 的安全性。