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Development of acute myeloid leukemia with NPM1 mutation, in Ph-negative clone, during treatment of CML with imatinib.

作者信息

Georgiou G, Efthymiou A, Vardounioti I, Boutsikas G, Angelopoulou M K, Vassilakopoulos T P, Kyrtsonis M-C, Plata E, Tofas P, Bitsani A, Bartzi V, Pessach I, Dimou M, Panayiotidis P

出版信息

Leukemia. 2012 Apr;26(4):824-6. doi: 10.1038/leu.2011.280. Epub 2011 Oct 11.

DOI:10.1038/leu.2011.280
PMID:21986839
Abstract
摘要

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Case Report of acute myeloid leukemia with "WT1, ATRX, CEBPA, CSMD1, IKZF1, and LRP1B mutation and translocation between chromosome 1 and 19" developing from Philadelphia-negative chronic myeloid leukemia after TKI therapy.TKI治疗后由费城阴性慢性髓系白血病发展而来的伴有“WT1、ATRX、CEBPA、CSMD1、IKZF1和LRP1B突变以及1号和19号染色体易位”的急性髓系白血病病例报告
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Leuk Res Rep. 2016 Jan 12;5:7-10. doi: 10.1016/j.lrr.2016.01.002. eCollection 2016.
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