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[硫酸肼制剂的临床研究结果]

[The results of a clinical study of the preparation hydrazine sulfate].

作者信息

Filov V A, Danova L A, Gershanovich M L, Ivin B A, Dement'eva N P, Breĭvis P V, Ragaĭshene V P, Kas'ianenko I V, Lisitsa A M, Mindlin S S

出版信息

Vopr Onkol. 1990;36(6):721-6.

PMID:2198698
Abstract

The paper discusses results of a cooperative study of effectiveness of hydrazine sulfate therapy in 740 patients with primary advanced, recurrent and metastatic solid tumors and malignant lymphomas who had failed all other treatment modalities. Both objective response and symptomatic effect were assessed. Objective response was observed in neuroblastoma, recurrent desmoid, Hodgkin's disease, lung cancer, fibrosarcoma and other tumors. Since hydrazine sulfate provided relief of a wide spectrum of cancer symptoms, it may be recommended for patients with end-stage cancer.

摘要

本文讨论了对740例原发性晚期、复发性和转移性实体瘤及恶性淋巴瘤患者进行的硫酸肼治疗效果的合作研究结果,这些患者对所有其他治疗方式均无效。评估了客观反应和症状效果。在神经母细胞瘤、复发性硬纤维瘤、霍奇金病、肺癌、纤维肉瘤和其他肿瘤中观察到了客观反应。由于硫酸肼能缓解多种癌症症状,因此可推荐给晚期癌症患者。

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