Cotrim Carolina Porto, Simone Fernanda Tolstoy de, Lima Ricardo Barbosa, Barcaui Carlos Baptista, Sousa Maria Auxiliadora Jeunon, Lowy Gabriela
Hospital Universitário Gaffrée e Guinle, Universidade Federal do Estado do Rio de Janeiro, Brasil.
An Bras Dermatol. 2011 Jul-Aug;86(4):767-71. doi: 10.1590/s0365-05962011000400023.
Acquired melanocytic lesions resembling malignant melanoma have been described in all major categories of Epidermolysis bullosa and referred to as "Epidermolysis bullosa nevi''. They easily induce to diagnostic error, although no malignant transformation has been reported. We report the development of a large acquired melanocytic nevus at a site of recurrent blisters in a 5-year-old child with Epidermolysis bullosa simplex. The global dermoscopic pattern was suggestive of benignity, and the histopathological findings were compatible with a compound melanocytic nevus. This is the first published case of Epidermolysis bullosa nevi in Brazilian literature. Despite their benign behavior, we emphasize the importance of regular clinical and dermoscopic monitoring, since a malignant course still cannot be totally excluded.
在所有主要类型的大疱性表皮松解症中均有类似恶性黑色素瘤的获得性黑素细胞病变的描述，被称为“大疱性表皮松解症痣”。尽管尚未有恶变的报道，但它们很容易导致诊断错误。我们报告了一名5岁单纯性大疱性表皮松解症患儿在反复出现水疱的部位出现一个巨大的获得性黑素细胞痣。整体皮肤镜表现提示为良性，组织病理学结果与复合性黑素细胞痣相符。这是巴西文献中首次发表的大疱性表皮松解症痣病例。尽管其行为良性，但我们强调定期临床和皮肤镜监测的重要性，因为仍不能完全排除恶变的可能。
