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新生儿先天性自愈性网状组织细胞增生症(桥本-普利茨克病)

Congenital self healing reticulohistiocytosis in a newborn (Hashimoto Pritzker).

作者信息

Orle Joana, Mósca Ana Maria, Sousa Maria Auxiliadora Jeunon, Lima Cíntia Maria Oliveira, Adriano André Ricardo, Rezende Patrícia Makino

机构信息

Policlínica Geral do Rio de Janeiro, Instituto de Pós-Graduação Médica Carlos Chagas, Rio de Janeiro, Brasil.

出版信息

An Bras Dermatol. 2011 Jul-Aug;86(4):785-8. doi: 10.1590/s0365-05962011000400026.

Abstract

Congenital self-healing reticulohistiocytosis is the benign spectrum of Langerhans Cell Histiocytosis, characterized by cutaneous lesions at birth or in the neonatal period, absence of systemic manifestations and spontaneous resolution of clinical status. Despite the benign and often self-resolving course in most patients, studies show that in some cases there may be metastasis or recurrence of the disease, emphasizing that the clinical course is variable, requiring long-term follow-up. The monitoring of the patient for a long period is important to detect possible systemic involvement, as there is a report of recurrence involving the skin, mucosa, bone and pituitary gland.

摘要

先天性自愈性网状组织细胞增生症是朗格汉斯细胞组织细胞增生症的良性类型,其特征为出生时或新生儿期出现皮肤病变,无全身表现且临床状况可自发缓解。尽管大多数患者病程呈良性且常可自愈,但研究表明,在某些情况下该病可能会转移或复发,这强调了临床病程具有变异性,需要长期随访。对患者进行长期监测对于发现可能的全身受累情况很重要,因为有报告称复发累及皮肤、黏膜、骨骼和垂体。

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