Crombleholme T M, Adzick N S, deLorimier A A, Longaker M T, Harrison M R, Charlton V E
Department of Surgery, University of California, San Francisco.
Am J Dis Child. 1990 Aug;144(8):872-4. doi: 10.1001/archpedi.1990.02150320036021.
Right hemispheric brain injury has been noted in surviving infants treated with venoarterial extracorporeal membrane oxygenation (ECMO). This phenomenon may be secondary to permanent ligation of the right carotid artery. At our institution, conventional ventilatory therapy failed in five neonates with respiratory insufficiency, and they were treated successfully with ECMO. In four of the five neonates, the right carotid artery was reconstructed at the time of decannulation. At discharge, all newborns with carotid artery repair showed no signs of unilateral brain injury and had excellent antegrade flow in the right carotid artery as assessed by both duplex and transcranial Doppler ultrasound scanning. Carotid artery reconstruction after ECMO is a technically simple procedure that may reduce the incidence of right hemispheric brain injury and long-term consequences of marginal cerebral perfusion.
在接受静脉-动脉体外膜肺氧合(ECMO)治疗后存活的婴儿中,已发现存在右半球脑损伤。这种现象可能继发于右颈动脉的永久性结扎。在我们机构,常规通气治疗对5例呼吸功能不全的新生儿无效,他们接受ECMO治疗后成功康复。5例新生儿中有4例在拔管时进行了右颈动脉重建。出院时,所有接受颈动脉修复的新生儿均未出现单侧脑损伤迹象,经双功超声和经颅多普勒超声扫描评估,右颈动脉有良好的顺行血流。ECMO术后的颈动脉重建是一种技术上简单的手术,可能会降低右半球脑损伤的发生率以及脑灌注不足的长期后果。