与居家老年患者使用抗抑郁药相关的人口统计学、临床和功能因素。
Demographic, clinical, and functional factors associated with antidepressant use in the home healthcare elderly.
机构信息
Department of Psychiatry, Weill Cornell Medical College, White Plains, NY 10601, USA.
出版信息
Am J Geriatr Psychiatry. 2011 Dec;19(12):1042-5. doi: 10.1097/JGP.0b013e318235b743.
OBJECTIVES
Determine rates and demographic, clinical, and functional correlates of antidepressants (ADs) in home healthcare patients.
METHODS
Year 2007 cross-sectional National Home Health and Hospice Care Survey (N = 3,226) of patients 65 years or older (mean 80.11, confidence interval [CI] = 79.65-80.57).
RESULTS
Overall 33.50% used ADs. Among the 6.76% with depression, 70.84% used ADs compared with 29.15% who used ADs without a documented depression diagnosis. In a regression, controlling for depression, blacks used less ADs than whites (odds ratio [OR] = 0.41, CI = 0.24-0.70). Younger age (OR = 0.96, CI = 0.94-0.98), activities of daily living impairments (OR = 1.15, CI = 1.05-1.26), benzodiazepines (OR = 2.63, CI = 1.88-3.69), antipsychotics (OR = 2.08, CI = 1.29-3.36), and nonpsychotropics (OR = 1.07, CI = 1.04-1.10) were related to AD use.
CONCLUSION
Among home healthcare patients, more than one-third took ADs including patients without depression. Blacks used fewer ADs than whites. Increased use was associated with younger age, disability, and nonpsychotropics.
目的
确定家庭保健患者中抗抑郁药（ADs）的使用率以及人口统计学、临床和功能相关性。
方法
2007 年对 65 岁及以上患者（平均年龄 80.11，置信区间 [CI] = 79.65-80.57）进行的全国家庭保健和临终关怀调查（N = 3226）的年度横断面研究。
结果
总体而言，有 33.50%的患者使用 ADs。在有抑郁症状的 6.76%的患者中，70.84%的患者使用 ADs，而有抑郁症状但未确诊的患者中，使用 ADs 的比例为 29.15%。在控制抑郁症状的回归分析中，黑人使用 ADs 的比例低于白人（比值比 [OR] = 0.41，CI = 0.24-0.70）。年龄较小（OR = 0.96，CI = 0.94-0.98）、日常生活活动受损（OR = 1.15，CI = 1.05-1.26）、苯二氮䓬类药物（OR = 2.63，CI = 1.88-3.69）、抗精神病药物（OR = 2.08，CI = 1.29-3.36）和非精神药物（OR = 1.07，CI = 1.04-1.10）与 ADs 的使用相关。
结论
在家庭保健患者中，超过三分之一的患者服用 ADs，包括没有抑郁症状的患者。黑人使用 ADs 的比例低于白人。年龄较小、残疾和使用非精神药物与 ADs 的使用增加相关。
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