Pharmacopsychiatry. 2011 Nov;44(7):346-7. doi: 10.1055/s-0031-1284429. Epub 2011 Oct 11.
A case of pharmacoresistant convulsions after selegiline overdose is reported. A 50-year-old male having been suffering from bipolar II disorder for 16 years attempted suicide by taking an overdose of 195 mg selegiline with other psychotropics. He developed recurrent pharmacoresistant seizure from 12th day to 19th day after selegiline overdose. He also had visual hallucinations and temporary high blood pressure. The authors suspect that the catecholamine-influenced convulsions and visual hallucinations that manifested during the period increased by the MAO-inhibiting action of selegiline which lasts about 2 weeks.
报告了一例司来吉兰过量引起的耐药性惊厥病例。一名 50 岁男性患有双相情感障碍 II 型 16 年，曾试图服用 195 毫克司来吉兰和其他精神药物过量自杀。他在司来吉兰过量后第 12 天至第 19 天反复发作耐药性惊厥。他还出现了幻视和一过性高血压。作者怀疑在司来吉兰的 MAO 抑制作用（持续约 2 周）期间，表现出的儿茶酚胺影响的惊厥和幻视增加。
