Department of Otolaryngology, Division of Head and Neck Surgery, Massachusetts Eye and Ear Infirmary, Boston, Massachusetts, USA.
Head Neck. 2011 Nov;33(11):1576-80. doi: 10.1002/hed.21632. Epub 2010 Dec 16.
The purpose of this study was to compare the tissue effects of 3 surgical methods of glossectomy with respect to histopathologic assessment by a pathologist.
The anterior tongue of 30 Sprague-Dawley rats was excised using either a steel scalpel, monopolar electrosurgery, or ultrasonic scalpel (3 groups of 10). Specimens were examined by a pathologist blinded to the surgical procedure, using a previously described grading system for margin artifact assessment.
Minimal tissue disruption at the surgical margin was produced by the steel scalpel, in contrast to monopolar electrosurgery and ultrasonic scalpel, which both produced varying levels of tissue distortion. Margin fragmentation was significantly greater with monopolar electrosurgery when compared to an ultrasonic scalpel.
Ultrasonic scalpel creates less tissue distortion at the surgical margin than monopolar electrosurgery. Further study is required to determine the clinical relevance of these findings.
本研究旨在通过病理学家的组织病理学评估，比较 3 种舌根切除术的组织效果。
使用钢刀、单极电刀或超声刀（每组 10 只）切除 30 只斯普拉格-道利大鼠的前舌。标本由一位对手术过程不知情的病理学家使用以前描述的用于评估边缘伪影的分级系统进行检查。
与单极电刀和超声刀相比，钢刀在手术边缘产生的组织破坏最小，而单极电刀和超声刀都产生了不同程度的组织变形。与超声刀相比，单极电刀的边缘碎片明显更多。
超声刀在手术边缘产生的组织变形小于单极电刀。需要进一步研究以确定这些发现的临床相关性。
