Interventional Neuroradiology and Endovascular Neurosurgery, Massachusetts General Hospital, Boston, MA 02114, USA.
J Neurointerv Surg. 2012 Mar;4(2):134-8. doi: 10.1136/jnis.2011.004879. Epub 2011 Apr 6.
To evaluate the safety and effectiveness of percutaneous acetabuloplasty in treating the pain and disability related to metastatic lesions of the acetabulum.
This institutional review board approved retrospective study examined 11 patients who underwent percutaneous acetabuloplasty in our hospital from April 2007 to June 2010. All patients gave informed consent prior to the procedure, and all records were HIPAA compliant. Chart review was performed to collect patient demographics and to assess pre- and post-treatment patient performance on the Visual Analog Scale, Functional Mobility Scale and Analgesic Scale. Paired testing comparing the pre- and post-treatment scores for each patient was performed using the Wilcoxon signed rank test.
There were 11 procedures: 10 performed under CT guidance and one using fluoroscopic guidance. There was a statistically significant decrease in patient Visual Analog Scale score (p=0.001) and Functional Mobility Scale score (p=0.03) after treatment. There was no change in median Analgesic Scale scores pre- and post-treatment although paired testing revealed a trend towards reduced analgesic use postoperatively (p=0.06). There were no clinically significant complications in this series.
Percutaneous acetabuloplasty appears to be safe and effective for improving the pain and decreased mobility secondary to metastatic lesions of the acetabulum.
评估经皮髋臼成形术治疗髋臼转移瘤相关疼痛和功能障碍的安全性和有效性。
本研究为机构审查委员会批准的回顾性研究，纳入了 2007 年 4 月至 2010 年 6 月在我院接受经皮髋臼成形术的 11 例患者。所有患者均在手术前签署了知情同意书，且所有病历均符合 HIPAA 规定。通过病历回顾收集患者的人口统计学数据，并评估患者在视觉模拟量表、功能移动量表和镇痛量表上的术前和术后表现。使用 Wilcoxon 符号秩检验对每位患者的术前和术后评分进行配对检验。
共进行了 11 例手术：10 例在 CT 引导下进行，1 例在透视引导下进行。治疗后患者的视觉模拟量表评分（p=0.001）和功能移动量表评分（p=0.03）均有统计学显著下降。尽管配对检验显示术后镇痛药物使用呈下降趋势（p=0.06），但中位数镇痛量表评分在术前和术后无变化。本系列中无临床显著并发症。
经皮髋臼成形术治疗髋臼转移瘤引起的疼痛和活动度下降是安全有效的。
