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使用可脱卸铂金纤维圈栓塞术治疗鼻出血的结果。

Results of epistaxis embosurgery using detachable platinum fibered coils.

机构信息

Department of Radiology, Scott & White Clinic, Temple, Texas, USA.

出版信息

J Neurointerv Surg. 2010 Jun;2(2):171-5. doi: 10.1136/jnis.2009.001834.

Abstract

BACKGROUND

Safety and efficacy outcomes are lacking for embosurgery of the distal internal maxillary artery (IMax) using detachable platinum fibered coils (DPFCs) in patients with uncontrollable epistaxis.

METHODS

A retrospective analysis was conducted on patients treated October 2006 through May 2009 with a diagnosis of uncontrollable or recurrent epistaxis managed by DPFC. Inclusion criteria included patients with epistaxis complicating open or endoscopic nasal surgery, or patients with the following covariant risk factors: aspirin, clopidogrel, warfarin, ibuprofen or hypertension. Patients were excluded if particulates, liquid glue or non-permanent embolics were used as adjuvants. Medical record review and follow-up for 1 month were performed on all patients to determine treatment results and complications.

RESULTS

A cohort of 20 patients meeting enrollment criteria was comprised of 13 men and 7 women with a mean age of 63 years (range 35-85 years). Epistaxis etiologies included recent nasal surgery (N=2) while all patients (N=20) had one or more covariant epistaxis risk factors. 17 patients underwent bilateral IMax embolization. Three patients had unilateral IMax embosurgery in which two patients had a remote history of contralateral IMax open ligation for previous epistaxis. 95% of the cohort remained free of recurrent nose bleeding requiring medical or surgical intervention. 95% of the patients had no complications while one patient (5%) had transient unilateral facial pain. There was no procedure-related death, blindness or stroke. One patient died during follow-up from unrelated causes.

CONCLUSION

DPFC embosurgery is effective and safe in managing uncontrollable epistaxis.

摘要

背景

对于无法控制的鼻出血患者,使用可分离铂金纤维圈(DPFC)栓塞内上颌动脉远段(IMax)的安全性和疗效数据尚缺乏。

方法

回顾性分析了 2006 年 10 月至 2009 年 5 月期间,使用 DPFC 治疗无法控制或复发性鼻出血的患者。纳入标准包括:鼻出血合并开放性或内镜鼻窦手术的患者;或存在以下伴发风险因素的患者:阿司匹林、氯吡格雷、华法林、布洛芬或高血压。如果使用颗粒、液体胶或非永久性栓塞物作为辅助治疗,则排除患者。对所有患者进行病历回顾和 1 个月随访,以确定治疗结果和并发症。

结果

符合纳入标准的患者队列共有 20 例,其中 13 例为男性,7 例为女性,平均年龄为 63 岁(35-85 岁)。鼻出血的病因包括近期鼻部手术(N=2),而所有患者(N=20)均存在 1 个或多个伴发的鼻出血风险因素。17 例患者行双侧 IMax 栓塞术,3 例患者行单侧 IMax 栓塞术,其中 2 例患者曾因先前的鼻出血而行对侧 IMax 开放结扎术。95%的患者未再出现需医疗或手术干预的复发性鼻出血,95%的患者无并发症,1 例(5%)患者出现短暂性单侧面部疼痛。无与手术相关的死亡、失明或中风病例,1 例患者在随访期间死于非相关原因。

结论

DPFC 栓塞术治疗无法控制的鼻出血有效且安全。

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