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动脉栓塞术在治疗鼻后段鼻出血中的应用

Arterial embolization in the management of posterior epistaxis.

作者信息

Christensen Nathan P, Smith Dana S, Barnwell Stanley L, Wax Mark K

机构信息

Department of Otolaryngology-Head and Neck Surgery, Oregon Health & Science University, Portland, OR 97239, USA.

出版信息

Otolaryngol Head Neck Surg. 2005 Nov;133(5):748-53. doi: 10.1016/j.otohns.2005.07.041.

Abstract

OBJECTIVES

Treatment of severe epistaxis can encompass many modalities. Control rates with all treatments are good. Morbidity among treatment groups varies. Angiographic embolization is one such method that has a very low complication rate. Over the last 10 years, it has become the preferred treatment at our institution.

STUDY DESIGN

Tertiary medical referral centers: OHSU, Portland VAMC.

MATERIALS AND METHODS

Retrospective review of 70 patients transferred or admitted with posterior epistaxis and treated with selective angiographic embolization from 1993 to 2002.

RESULTS

Patients had bleeding for a median of 4.5 days prior to admission. 79% were unilateral. Etiology of bleeding was: idiopathic (61%), previous surgery (11%), anticoagulants (9%), trauma (7%), and other causes (12%). 30% required blood transfusions prior to admission to OHSU (average 4.4 units). No patient required a transfusion postoperatively following angiographic embolization or during their hospitalization. The internal maxillary artery (IMAX) was embolized in 94% (47% unilateral or bilateral IMAX only, 47% unilateral or bilateral IMAX in combination with other vessels, 6% other vessels besides the IMAX). Mean length of stay was 2.5 days. 86% had minor or no complications after the embolization and were discharged within 24 hours. 13% had a major rebleed that required surgical intervention within 6 weeks of the embolization. One patient had a serious neurological complication. Using the data available on 68 of 70 patients, the cost of hospitalization averaged dollar 18,000 with direct costs of embolization averaging dollar 11,000.

CONCLUSIONS

Angiographic embolization is a clinically effective treatment for severe epistaxis.

EBM RATING

C.

摘要

目的

严重鼻出血的治疗方法多种多样。所有治疗方法的控制率都不错。各治疗组的发病率有所不同。血管造影栓塞术就是这样一种并发症发生率极低的方法。在过去10年里,它已成为我们机构的首选治疗方法。

研究设计

三级医疗转诊中心:俄勒冈健康与科学大学(OHSU)、波特兰退伍军人医疗中心(Portland VAMC)。

材料与方法

对1993年至2002年期间因后鼻孔出血而转诊或入院并接受选择性血管造影栓塞治疗的70例患者进行回顾性研究。

结果

患者入院前出血的中位时间为4.5天。79%为单侧出血。出血病因包括:特发性(61%)、既往手术史(11%)、抗凝剂使用(9%)、外伤(7%)以及其他原因(12%)。30%的患者在入住OHSU前需要输血(平均4.4单位)。血管造影栓塞术后或住院期间,没有患者需要输血。94%的患者栓塞了上颌内动脉(IMAX)(47%仅单侧或双侧IMAX,47%单侧或双侧IMAX联合其他血管,6%为IMAX以外的其他血管)。平均住院时间为2.5天。86%的患者栓塞后出现轻微并发症或无并发症,并在24小时内出院。13%的患者出现严重再出血,需要在栓塞后6周内进行手术干预。1例患者出现严重的神经并发症。根据70例患者中68例的可用数据,住院费用平均为18,000美元,栓塞的直接费用平均为11,000美元。

结论

血管造影栓塞术是治疗严重鼻出血的一种临床有效方法。

循证医学评级

C级

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