经血管造影证实的左侧大脑中动脉栓塞性卒中在动脉内溶栓治疗期间发生出血性转化。
Angiographically documented hemorrhagic conversion of a left middle cerebral artery embolic stroke during intra-arterial thrombolysis.
机构信息
Rhode Island Hospital, Department of Diagnostic Imaging, Division of Interventional Radiology, 593 Eddy Street, Providence, Rhode Island 02903, USA.
出版信息
J Neurointerv Surg. 2011 Sep;3(3):246-8. doi: 10.1136/jnis.2010.003459. Epub 2010 Dec 8.
BACKGROUND AND PURPOSE
The clinical benefits of intra-arterial thrombolysis for ischemic stroke must be weighed against the risks, including hemorrhagic conversion.
SUMMARY OF CASE
A case of angiographically documented hemorrhagic conversion of an ischemic stroke during intra-arterial thrombolysis is presented. Discussion focuses on recognition and management of risk factors for hemorrhagic conversion during performance of stroke thrombolysis.
CONCLUSIONS
Recognition and modification of risk factors for hemorrhagic conversion may not prevent this complication during stroke thrombolysis. Identification of the angiographic appearance of hemorrhagic conversion should alert the interventionalist to the likelihood of a poor clinical outcome regardless of vessel patency status.
背景与目的
必须权衡经动脉溶栓治疗缺血性脑卒中的临床获益与风险，包括出血性转化。
病例概述
本文报道了一例经动脉溶栓治疗期间发生的缺血性脑卒中的血管造影证实的出血性转化病例。讨论重点是在进行脑卒中溶栓治疗时识别和管理出血性转化的危险因素。
结论
在脑卒中溶栓治疗期间，识别和改变出血性转化的危险因素可能无法预防这种并发症。出血性转化的血管造影表现的识别应提醒介入医生，无论血管通畅情况如何，临床预后均可能较差。
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