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The Treatment of Lyell'S Syndrome: our Experience.

作者信息

Napoli B, D'Arpa N, Masellis M

机构信息

Plastic Surgery and Burns Therapy Operating Unit, ARNAS Civic Hospital, Palermo, Italy.

出版信息

Ann Burns Fire Disasters. 2006 Mar 31;19(1):33-5.

Abstract

In view of the pathogenic mechanisms of Lyell's syndrome, we consider support-only treatment to be insufficient and believe it is necessary to administer i.v. human immunoglobulin. Because of the potentially severe side effects of the high doses usually recommended, we prefer to use low doses (no more than 5 g per day) in association with the administration of fresh frozen plasma, which offers the benefits of the high protein content in the albumin (with its resuscitatory function) and its globulin content (functioning as a specific therapy for Lyell's syndrome). We present the latest cases we have observed and treated using this protocol.

摘要

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