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混合皮肤移植:一种低成本的有效移植方法。

Intermingled skin grafting: a valid transplantation method at low cost.

作者信息

Domres B, Kistler D, Rutczynska J

机构信息

Department of Surgery and Institute of Pathology, University Hospital Tübingen, Germany.

出版信息

Ann Burns Fire Disasters. 2007 Sep 30;20(3):149-54.

Abstract

The almost forgotten method of intermingled skin grafting of allogeneic material with small autogeneic islets, once developed in the People's Republic of China, proves the feasibility of permanent healing of even extensive burn wounds, at low cost, and therefore an effective treatment possibility in poorer countries, as well as under conditions of a burn disaster. Intermingled skin grafting obtains a better elasticity of the reconditioned skin as elastic fibres of the allodermis survive, and this results in fewer contractures. From the cosmetic point of view the transplantation of autologous keratinocytes results in a better aesthetic homogeneous texture.

摘要

中华人民共和国曾经研发的将异体材料与小剂量自体胰岛混合植皮这一几乎被遗忘的方法,证明了即使是大面积烧伤创面也能以低成本实现永久愈合,因此在较贫穷国家以及烧伤灾难情况下是一种有效的治疗可能性。混合植皮可使修复后的皮肤具有更好的弹性,因为异体真皮的弹性纤维得以存活,从而减少挛缩。从美容角度来看,自体角质形成细胞移植可产生更美观的均匀质地。

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本文引用的文献

1
Dermagraft-TC pivotal efficacy and safety study.Dermagraft-TC关键疗效与安全性研究。
J Burn Care Rehabil. 1997 Jan-Feb;18(1 Pt 2):S13-4. doi: 10.1097/00004630-199701001-00007.
3
5
Morphological changes of intermingled skin transplants on rats.大鼠混合皮肤移植的形态学变化
Burns Incl Therm Inj. 1988 Apr;14(2):115-9. doi: 10.1016/0305-4179(88)90215-x.
8
Keratinocyte grafts and skin equivalents.角质形成细胞移植和皮肤替代物。
Int J Dermatol. 1991 Aug;30(8):540-51. doi: 10.1111/j.1365-4362.1991.tb02636.x.

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