Kim Daesung, Kang Taeheon, Gober Daniel, Orlich Chad
College of Dentistry, Ewha Womans University, Seoul 158-710, Republic of Korea.
ISRN Dent. 2011;2011:468282. doi: 10.5402/2011/468282. Epub 2011 Jun 12.
Membranes made of several different materials are available in the market, nonresorbable (e.g. ePTFE), resorbable (e.g. synthetic or collagen) and liguid applicable (e.g. Polyethylene glycol or Atrisorb). The purpose of the present study was to evaluate whether or not in situ application of Atrisorb could be used as a barrier membrane for guided bone regeneration. Ten patients with insufficient alveolar ridge width for implant placement participated in the study. Atrisorb in conjunction with various bone grafts was used to treat 10 different sites, 3 sites treated prior to implant placement and 7 sites in conjunction with implant placement. Augmented sites were allowed to heal for 3 to 7 months, with mean healing time of 4.7 months. Healing was uneventful with no major complications. Two sites experienced a flap dehiscence accompanied by barrier exposure during the initial healing period. Secondary healing was achieved soon after with no signs of infection, giving Atrisorb a barrier exposure rate of 20% for the present study, which corresponds to favorably to that of resorbable membranes. The liquid membrane has the potential of being a viable alternative to traditional resorbable membranes for use in GBR procedures.
市场上有几种由不同材料制成的膜,不可吸收的(如ePTFE)、可吸收的(如合成材料或胶原蛋白)以及可液体应用的(如聚乙二醇或Atrisorb)。本研究的目的是评估原位应用Atrisorb是否可用作引导骨再生的屏障膜。10名牙槽嵴宽度不足以植入种植体的患者参与了该研究。Atrisorb与各种骨移植材料联合用于治疗10个不同部位,3个部位在植入种植体前进行治疗,7个部位与种植体植入同时进行。增加骨量的部位愈合3至7个月,平均愈合时间为4.7个月。愈合过程顺利,无重大并发症。在初始愈合期,有2个部位出现皮瓣裂开并伴有屏障膜暴露。随后很快实现二期愈合,无感染迹象,在本研究中Atrisorb的屏障膜暴露率为20%,这与可吸收膜的情况相当。这种液体膜有可能成为在引导骨再生手术中替代传统可吸收膜的可行选择。