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一项针对接受内镜手术的 CRS 患者生活质量和缺勤情况的多中心研究。

A multi-centre study on quality of life and absenteeism in patients with CRS referred for endoscopic surgery.

机构信息

Department of Otolaryngology, Head and Neck Surgery, Lund University, Malmo, Sweden.

出版信息

Rhinology. 2011 Oct;49(4):420-8. doi: 10.4193/Rhino11.101.

Abstract

AIMS

This study summarises the health-related quality of life (HRQOL) scores and absenteeism caused by sinus problems in patients awaiting surgery with the diagnoses recurrent acute rhinosinusitis (RARS), chronic rhinosinusitis with nasal polyps (CRS+NP) or CRS without nasal polyps (CRS-NP), in a prospective multi-centre study.

METHODOLOGY

Two hundred and seven patients with RARS, CRS+NP or CRS-NP were enrolled. EP3OS definitions of CRS and NP were used. The patients completed the 22 Sinonasal Outcome Test (SNOT-22), the short-form 36-item questionnaire (SF-36), the Hospital Anxiety and Depression Scale (HAD) and a total Visual Analogue Scale (VAS) regarding rhinosinusitis symptoms.

RESULTS

SNOT-22 and VAS scores indicated severe disease. Comparison of the HRQOL scores in the three rhinosinusitis subgroups showed statistical differences in nine of the SNOT-22 items and in the SF-36 subscale of bodily pain. Mean scores of SF-36 were significantly lower than that of the normal Swedish population. According to the HAD scores, 28% of the patients had probable or possible anxiety or depression disorder. Fifty-seven percent of the patients reported absenteeism from work due to sinus problems.

CONCLUSIONS

RARS, CRS+NP and CRS-NP significantly decrease HRQOL. Some statistically significant differences in HRQOL were found between the three rhinosinusitis subgroups. Absenteeism due to chronic sinus conditions is considerable.

摘要

目的

本研究总结了患有复发性急性鼻-鼻窦炎(RARS)、伴有鼻息肉的慢性鼻-鼻窦炎(CRS+NP)或不伴鼻息肉的慢性鼻-鼻窦炎(CRS-NP)的患者在等待手术时因鼻窦问题导致的健康相关生活质量(HRQOL)评分和缺勤情况。

方法

共纳入 207 例 RARS、CRS+NP 或 CRS-NP 患者。采用 EP3OS 对 CRS 和 NP 进行定义。患者完成 22 项鼻-鼻窦结局测试(SNOT-22)、简短 36 项健康调查(SF-36)、医院焦虑和抑郁量表(HAD)以及一项关于鼻-鼻窦炎症状的总视觉模拟量表(VAS)。

结果

SNOT-22 和 VAS 评分表明疾病严重。对三组鼻-鼻窦炎亚组的 HRQOL 评分进行比较,SNOT-22 的 9 项和 SF-36 躯体疼痛亚项的评分存在统计学差异。SF-36 的平均评分明显低于瑞典正常人群。根据 HAD 评分,28%的患者存在可能或确定的焦虑或抑郁障碍。57%的患者因鼻窦问题缺勤。

结论

RARS、CRS+NP 和 CRS-NP 显著降低 HRQOL。在三组鼻-鼻窦炎亚组之间发现了一些 HRQOL 的统计学差异。由于慢性鼻窦疾病导致的缺勤相当可观。

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