萘普生钠在肌肉骨骼疾病中的临床应用
[Clinical use of naproxen sodium in muscular skeletal disorders].
作者信息
Tang F S
机构信息
First Affiliated Hospital, Chongqing University of Medical Sciences, Sichuan.
出版信息
Zhonghua Wai Ke Za Zhi. 1990 Mar;28(3):167-70, 190.
Naproxen sodium is a new non-steroid antiinflammatory drug. This paper reported the results of clinical trial of the drug in 229 cases of orthopedic conditions. Among them, 103 cases were observed with double method. The rate of symptomatic relief was 81.3% (75 cases) for rheumatoid arthritis, 72.4% (29 cases) for osteoarthritis, 76.5% (34 cases) for herniations of lumbar discs and 93% (91 cases) for mild post-operative pain. The overall efficacy of the drug was 84.2% with 6.1% side effects, chiefly gastric reactions.
萘普生钠是一种新型非甾体抗炎药。本文报道了该药治疗229例骨科疾病的临床试验结果。其中，103例采用双盲法观察。类风湿性关节炎的症状缓解率为81.3%（75例），骨关节炎为72.4%（29例），腰椎间盘突出症为76.5%（34例），轻度术后疼痛为93%（91例）。该药的总有效率为84.2%，副作用发生率为6.1%，主要为胃肠道反应。
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