Bhomi K K, Rizal S, Pradhan M, Rijal A, Bhattachan C L
Department of Surgery, Nepal Medical College Teaching Hospital, Kathmandu, Nepal.
Nepal Med Coll J. 2011 Mar;13(1):55-7.
Lignocaine gel is an established topical anesthetic agent for cystoscopy in awake patients. We performed a prospective randomized study to evaluate whether cooling the lignocaine gel to 4 degrees C decreases the pain perception during cystoscopy in male patients. Sixty consecutive male patients undergoing rigid cystoscopy were randomized into two groups. Group I received 15 ml of 2% lignocaine hydrochloride gel at 4 degrees C and group II received the same agent at room temperature (20 degrees C). Cystoscopy was performed and pain perceived during the procedure was assessed by independent evaluator using Wong-Baker FACES pain scale rating chart. The mean pain score in group I was lower (4.32 +/- 1.70) than that in group II (5.28 +/- 1.99), but this difference was statistically not significant (p=0.191). However significantly greater percentage (84% Vs 52%) of patients with cooled lignocaine wished to have same anesthetic in future for similar procedure (p=0.032). In conclusion, cooling the lignocaine gel to 4 degrees C does not decrease the pain perception during rigid cystoscopy in male patients.
利多卡因凝胶是一种用于清醒患者膀胱镜检查的成熟局部麻醉剂。我们进行了一项前瞻性随机研究，以评估将利多卡因凝胶冷却至4摄氏度是否会降低男性患者膀胱镜检查期间的疼痛感知。连续60例接受硬性膀胱镜检查的男性患者被随机分为两组。第一组接受15毫升4摄氏度的2%盐酸利多卡因凝胶，第二组接受室温（20摄氏度）下的相同药物。进行膀胱镜检查，并由独立评估者使用面部表情疼痛量表评分图评估检查过程中感知到的疼痛。第一组的平均疼痛评分（4.32±1.70）低于第二组（5.28±1.99），但这种差异在统计学上不显著（p=0.191）。然而，使用冷却利多卡因的患者中希望在未来类似检查中使用相同麻醉剂的比例显著更高（84%对52%，p=0.032）。总之，将利多卡因凝胶冷却至4摄氏度不会降低男性患者硬性膀胱镜检查期间的疼痛感知。
