Choudhury Minati, Hote Milind P, Verma Yashwant
Department of Cardiac Anaesthesia, Cardiothoracic Sciences Centre, AIIMS, New Delhi 110029, India.
Middle East J Anaesthesiol. 2011 Feb;21(1):111-4.
Depression is common in patients with ischemic heart disease. According to mental health survey approximately one fifth of the patients with angiographic evidence of coronary artery disease have major depression. It is well recognized that stigmatization of mental disorders leads to stigmatized individuals to avoid treatment or to conceal treatment. We report a case of serotonin syndrome that occurred during postoperative period in a patient who underwent coronary artery bypass grafting. The patient was receiving 60 mg/day fluoxetine since the last four years which she and her attendants concealed during the preoperative evaluation. To our knowledge this is the first case in a postoperative patient reported in biomedical literature. We suggest that history taking should be done with special emphasis on antidepressant drug intake in patients suffering from coronary artery disease. If serotonin syndrome occurs in these patients aggressive and timely management can save the patient.
抑郁症在缺血性心脏病患者中很常见。根据心理健康调查,约五分之一有冠状动脉造影证据的冠心病患者患有重度抑郁症。人们普遍认识到,精神障碍的污名化会导致受污名化的个体避免治疗或隐瞒治疗情况。我们报告一例在冠状动脉搭桥术后发生血清素综合征的病例。该患者在过去四年中每天服用60毫克氟西汀,她和她的护理人员在术前评估时隐瞒了这一情况。据我们所知,这是生物医学文献中报道的术后患者中的首例。我们建议,在对冠心病患者进行病史采集时,应特别强调抗抑郁药物的服用情况。如果这些患者发生血清素综合征,积极及时的处理可以挽救患者生命。