Bio-Organic Division, Theoretical Chemistry Section, Bhabha Atomic Research Centre, Mumbai-400085, India.
Org Lett. 2011 Nov 4;13(21):5870-3. doi: 10.1021/ol202490p. Epub 2011 Oct 12.
Starting from some meso-methyl Bodipy dyes, the corresponding meso-styryl derivatives were synthesized by regioselective Knoevenagel-type condensation with different aromatic aldehydes. The reactions were driven by the alleviation of the structural strain of the alkyl substituted Bodipys that could override the differential acidities of the methyl protons at the pyrrole ring of the Bodipy moiety.
从一些中-甲基金属 Bodipy 染料出发，通过与不同芳香醛的区域选择性 Knoevenagel 型缩合反应合成了相应的中-苯乙烯基衍生物。反应是由取代的 Bodipy 部分的吡咯环上的甲基质子的不同酸度被烷基取代 Bodipys 的结构应变缓解所驱动的。
