Centre for Pharmaceutical Nanotechnology and Nanotoxicology, University of Copenhagen, Universitetsparken 2, DK-2100 Copenhagen Ø, Denmark.
ACS Nano. 2011 Nov 22;5(11):8454-8. doi: 10.1021/nn2038252. Epub 2011 Oct 12.
We present views on the future development of biologics-based nanopharmaceuticals from a "high risk-high gain" perspective and within the context of personalized therapies. Integrated scientific, commercial, and societal aspects are addressed, and provocative combined realistic biotech, computational, and nanotech approaches for tailor-made engineering of nanopharmaceuticals are discussed.
我们从“高风险高回报”的角度并结合个性化治疗的背景,对基于生物制剂的纳米药物的未来发展提出了看法。文中涉及到综合的科学、商业和社会方面,并讨论了具有挑战性的综合现实生物技术、计算和纳米技术方法,以实现纳米药物的定制工程。