Department of Internal Medicine, Royal Perth Hospital, Wellington Street, Perth, Western Australia 6000, Western Australia, Australia.
J Clin Neurosci. 2011 Dec;18(12):1716-8. doi: 10.1016/j.jocn.2011.03.024. Epub 2011 Oct 10.
Anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis usually presents with psychiatric symptoms, behavioural changes, impaired consciousness, seizures and autonomic instability. Ictal asystole is a rare phenomenon associated with complex partial seizures. It is implicated as a potential cause of sudden unexpected death in epilepsy. We report a 41-year-old woman who presented with anti-NMDAR encephalitis. During continuous video electroencephalogram and cardiac monitoring, an episode of ictal asystole was detected. We discuss the potential link between anti-NMDAR encephalitis and ictal asystole. Treatment options for ictal asystole in the setting of anti-NMDAR encephalitis are also discussed.
抗 N-甲基-D-天冬氨酸受体（NMDAR）脑炎通常表现为精神症状、行为改变、意识障碍、癫痫发作和自主神经不稳定。癫痫发作性心搏停止是与复杂部分性癫痫发作相关的罕见现象。它被认为是癫痫猝死的潜在原因。我们报告了一例 41 岁女性，表现为抗 NMDAR 脑炎。在连续视频脑电图和心脏监测期间，检测到一次癫痫发作性心搏停止。我们讨论了抗 NMDAR 脑炎与癫痫发作性心搏停止之间的潜在联系。还讨论了抗 NMDAR 脑炎背景下癫痫发作性心搏停止的治疗选择。
