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腹腔镜植入神经假体至骶丛治疗经皮骶神经刺激失败后的神经源性膀胱功能障碍。

The laparoscopic implantation of neuroprothesis to the sacral plexus for therapy of neurogenic bladder dysfunctions after failure of percutaneous sacral nerve stimulation.

机构信息

Department of Surgical Gynecology & Neuropelveology, Hirslanden Clinic, Zürich, Switzerland.

出版信息

Neuromodulation. 2010 Apr;13(2):141-4. doi: 10.1111/j.1525-1403.2009.00230.x. Epub 2009 Aug 24.

DOI:10.1111/j.1525-1403.2009.00230.x
PMID:21992790
Abstract

OBJECTIVES

To report about our first short series of laparoscopic implantation of neuroprothesis-LION procedure-to the sacral plexus for treatment of different neurogenic bladder dysfunctions in patients in whom percutaneous sacral nerve stimulation (SNS) failed.

MATERIAL AND METHODS

A unilateral sacral LION procedure was performed in four patients with a refractary interstitial cystitis, in 13 patients with refractory bladder overactivity (multiple sclerosis N= 8, spina bifida N= 1, incomplete paraplegia N= 2, diabetic cystopathy N= 1), one patient with a neurogenic bladder incontinence by Parkinson syndrome, and in four patients for treatment for bladder atonia (Fowler's syndrome). In all patients, not only previous medical treatments but also SNS by transforaminal implantation had failed. Laparoscopic exposure of the sacral nerves roots S2 to S4/5 is performed by a transperitoneal approach and a quad electrode is placed perpendicular to the sacral nerve roots for postoperative global stimulation of these sacral nerve roots.

RESULTS

All procedures were performed successfully by laparoscopy without any complications. The mean operative time for such a procedure was 34 min. In two patients of the series postoperative neuromodulation failed. In all further 19 patients with an actual follow-up varying between three months and three years, neuromodulation is still working successfully.

CONCLUSIONS

Our results underscore that the sacral LION procedure to the sacral plexus is effective and safe for treatment divers neurogenic bladder dysfunctions even after failure of the classical percutaneous technique of implantation.

摘要

目的

报告我们首例应用腹腔镜植入式神经刺激器(LION)-对骶丛行单侧骶神经刺激术(LION 术)治疗经皮骶神经刺激(SNS)失败后出现不同神经源性膀胱功能障碍患者的短期经验。

材料和方法

4 例间质性膀胱炎、13 例难治性膀胱过度活动症(多发性硬化症 8 例、脊膜膨出 1 例、不完全性截瘫 2 例、糖尿病性膀胱病 1 例)、1 例帕金森病神经源性膀胱失禁和 4 例膀胱弛缓症(Fowler 综合征)患者接受了单侧 LION 术。所有患者均经先前的药物治疗和经皮椎间孔 SNS 治疗失败。通过经腹腔途径对 S2 至 S4/5 骶神经根进行腹腔镜暴露,并将四电极垂直放置在骶神经根上,以对这些骶神经根进行术后全面刺激。

结果

所有手术均成功完成,无任何并发症。该手术的平均手术时间为 34 分钟。在该系列中的 2 例患者术后神经调节失败。在其余 19 例实际随访时间为 3 个月至 3 年的患者中,神经调节仍然有效。

结论

我们的结果强调,即使在经典经皮植入技术失败后,LION 术治疗各种神经源性膀胱功能障碍也是有效且安全的。

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