Sheridan R, Ratledge C, Chalk P A
Department of Applied Biology, University of Hull, U.K.
FEMS Microbiol Lett. 1990 May;57(1-2):165-9. doi: 10.1016/0378-1097(90)90432-p.
The supply of acetyl units from the mitochondrion to the cytosol of Candida albicans appears to be dependent only upon the activity of carnitine acetyltransferase (CAT). The enzyme ATP:citrate lyase (ACL), the major source of acetyl units in oleaginous yeasts, is absent from C. albicans in both the mycelial and yeast forms. There appears to be no other active translocation of acetate or acetyl groups except via the action of carnitine acetyltransferase.
白色念珠菌线粒体中乙酰基单位向胞质溶胶的供应似乎仅取决于肉碱乙酰转移酶(CAT)的活性。在产油酵母中作为乙酰基单位主要来源的ATP:柠檬酸裂解酶(ACL),在白色念珠菌的菌丝体和酵母形式中均不存在。除了通过肉碱乙酰转移酶的作用外,似乎不存在其他活跃的乙酸盐或乙酰基转运。