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现场记录:与山羊场有关的 Q 热疫情爆发——华盛顿州和蒙大拿州,2011 年。

Notes from the field: Q fever outbreak associated with goat farms--Washington and Montana, 2011.

出版信息

MMWR Morb Mortal Wkly Rep. 2011 Oct 14;60(40):1393.

Abstract

On April 22, 2011, the Q fever bacterium Coxiella burnetii was detected in a goat placenta collected from a farm in Washington, where 14 of 50 (28%) pregnant does had aborted since January. A county health alert advised health-care providers to ask patients with symptoms compatible with Q fever (e.g., fever, headache, chills, and myalgia) about exposure to goats, and the owners of the farm informed purchasers of their goats that C. burnetii had been detected in their herd. On May 25, the county health department reported a symptomatic patient with antibodies to C. burnetii who had purchased goats from the farm in February. On May 27, a report from Montana identified a child seropositive for C. burnetii whose family had purchased goats from the Washington farm in October 2010; one of the goats aborted triplets 2 weeks before the child's May 12, 2011, illness onset. On May 31, five more persons reported onset of symptoms compatible with Q fever from late March to mid-May, following exposure at a Montana farm to goats purchased from the Washington farm at various times during October 2010--January 2011. On June 10, the Washington State Department of Health and Montana Department of Public Health and Human Services requested CDC assistance to characterize the extent of the outbreak, distribute Q fever information, and identify others at risk for infection.

摘要

2011 年 4 月 22 日,从华盛顿州一个农场采集的山羊胎盘中检测到了 Q 热病原体贝氏柯克斯体。自 1 月以来,该农场 50 只(28%)妊娠母羊中有 14 只流产。县卫生部门发布健康警报,建议卫生保健提供者询问有 Q 热(如发热、头痛、寒战和肌痛)症状的患者是否接触过山羊,该农场的主人通知其山羊的购买者,在他们的羊群中检测到了贝氏柯克斯体。5 月 25 日,该县卫生部门报告了一名有症状的患者,其对 C. burnetii 具有抗体,他曾于 2 月从该农场购买过山羊。5 月 27 日,蒙大拿州的一份报告确定了一名 C. burnetii 血清阳性的儿童,其家人于 2010 年 10 月从华盛顿州的农场购买了山羊;在该儿童于 2011 年 5 月 12 日发病前 2 周,其中一只山羊流产了三胞胎。5 月 31 日,又有 5 人报告称,自 3 月下旬至 5 月中旬,在蒙大拿州的一个农场接触了 2010 年 10 月至 2011 年 1 月期间从华盛顿州农场购买的山羊后,出现了与 Q 热相符合的症状。6 月 10 日,华盛顿州卫生部和蒙大拿州公共卫生和人类服务部请求疾病预防控制中心协助确定疫情范围,分发 Q 热信息,并确定其他有感染风险的人。

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