Magrabi Eye Hospital, Dubai Healthcare City, Saudi Arabia.
Cornea. 2011 Dec;30(12):1502-9. doi: 10.1097/ICO.0b013e31822018b9.
To demonstrate the efficacy of a planned near-Descemet dissection deep anterior lamellar keratoplasty (nddDALK) in posthydrops corneal scarring.
In a retrospective noncomparative case series, nddDALK was performed on 22 consecutive eyes of 22 patients with posthydrops scarring because of keratoconus. After a partial thickness corneal trephination, air was injected at superficial to midstromal depth, followed by an anterior keratectomy. Multiple episodes of stromal hydration with a blunt cannula followed by air injection were repeated to leave a thin stromal layer. A #69 Beaver blade (BD, Franklin Lakes, NJ) was used to remove the scar. The best spectacle-corrected visual acuity (BSCVA), spherical equivalent, and refractive cylinder were recorded 12, 24, and 36 months after surgery. Intraoperative and postoperative complications were noted.
Twelve months after surgery, the BSCVA was ≥ 20/40 in 68.1% of patients. The mean spherical equivalent was -3.53 ± 2.94 diopters (D), and the average refractive cylinder was 3.42 ± 1.7 D. Microperforations occurred in 6 patients, all of which were successfully tamponaded by an intracameral air injection alone.
nddDALK gives good visual results and quality of vision. In developing countries, lamellar-grade donor corneas are almost the only option available. Apart from visual benefits, the procedure puts the patient at a minimal risk of immune rejection, which is a major complication of penetrating keratoplasty.
展示计划行近 Descemet 膜解剖性深板层角膜移植术(nddDALK)在眼后弹力层膨出性角膜病变瘢痕中的疗效。
本回顾性非对照病例系列研究纳入了 22 例圆锥角膜眼后弹力层膨出性瘢痕患者(共 22 只眼),对其施行 nddDALK。行角膜部分厚度环钻切开后,于浅基质层至中基质层间注入空气,随后行角膜前层切除术。使用钝套管多次进行基质水化并重复注入空气,以保留较薄的基质层。使用#69 号 Beaver 刀片(BD,富兰克林湖,新泽西州)切除瘢痕。术后 12、24 和 36 个月时记录最佳矫正视力(BSCVA)、等效球镜和屈光柱。记录术中及术后并发症。
术后 12 个月时,68.1%的患者 BSCVA≥20/40。平均等效球镜为-3.53±2.94 屈光度(D),平均屈光柱为 3.42±1.7 D。6 例患者发生微穿孔,均通过单纯眼内空气注射成功填塞。
nddDALK 可获得良好的视力和视觉质量。在发展中国家,板层供体角膜几乎是唯一的选择。除了视力获益外,该手术使患者发生免疫排斥反应的风险降至最低,免疫排斥反应是穿透性角膜移植术的主要并发症之一。